Detalhe da pesquisa
1.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 184(18): 4651-4668.e25, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450028
2.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 187(6): 1565-1566, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490183
3.
Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants.
Clin Transl Sci
; 17(1): e13690, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38010108
4.
Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia.
bioRxiv
; 2024 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405775
5.
Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I/Ib studies in healthy subjects and patients.
Clin Transl Sci
; 15(8): 2010-2023, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35649245
6.
Longitudinal biomarkers in amyotrophic lateral sclerosis.
Ann Clin Transl Neurol
; 7(7): 1103-1116, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32515902